S-(-)-NICOTINE-D1'-(5')-IMINIUM DIPERCHLORATE SALT

Base Information

• Chemical Name: S-(-)-NICOTINE-D1'-(5')-IMINIUM DIPERCHLORATE SALT
• CAS No.: 71014-67-0
• Molecular Formula: C₁₀H₁₃N₂*ClHO₄*ClO₄
• Molecular Weight: 361.136
• Mol file: 71014-67-0.mol

Synonyms:

Chemical Property of S-(-)-NICOTINE-D1'-(5')-IMINIUM DIPERCHLORATE SALT

Chemical Property:

• Melting Point: 228-232°C

Purity/Quality:

97% ^*data from raw suppliers

S-(-)-Nicotine-Δ1’(5’)-iminiumDiperchlorateSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: An intermediary metabolite of Nicotine S-(-)-Nicotine-Δ1’(5’)-iminium diperchlorate is an intermediate in the synthesis of Nicotine (N412420) metabolites.

Technology Process of S-(-)-NICOTINE-D1'-(5')-IMINIUM DIPERCHLORATE SALT

There total 4 articles about S-(-)-NICOTINE-D1'-(5')-IMINIUM DIPERCHLORATE SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-Cyanonicotine (42459-12-1,56942-43-9,56942-44-0) → (S)-nicotine Δ-1',5'-iminium bisperchlorate (71014-67-0)

Guidance literature:

With perchloric acid; In ethanol; Yield given;

DOI:10.1021/jm00385a004

Reference yield:

(S)-1-Methyl-5-pyridin-3-yl-pyrrolidin-2-ol (1009088-33-8) → (S)-nicotine Δ-1',5'-iminium bisperchlorate (71014-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / AcOH / H₂O; diethyl ether

2: 70percent perchloric acid / ethanol

With perchloric acid; acetic acid; In diethyl ether; ethanol; water;

DOI:10.1021/jm00385a004

Reference yield:

nicotin (54-11-5) → (S)-nicotine Δ-1',5'-iminium bisperchlorate (71014-67-0)

Guidance literature:

Multi-step reaction with 2 steps

2: 70percent perchloric acid / ethanol

With perchloric acid; In ethanol;

DOI:10.1021/jm00385a004

upstream raw materials:

5'-Cyanonicotine

(S)-1-Methyl-5-pyridin-3-yl-pyrrolidin-2-ol

nicotin

cotinine

Refernces