Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester

Base Information

• Chemical Name: Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester
• CAS No.: 30167-07-8
• Molecular Formula: C₁₉H₃₆O₈S₂
• Molecular Weight: 456.622
• Mol file: 30167-07-8.mol

Synonyms:

Chemical Property of Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester

There total 4 articles about Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (1'S,4'aS,7'S,8'S,8'aR)-7'-isopropyl-1',4'a-dimethyl-octahydro-spiro[[1,3]dioxolane-2,2'-naphthalen]-8'-yl ester (30167-03-4) → Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester (30167-07-8)

Guidance literature:

Multi-step reaction with 4 steps

1: AcOH

2: (i) H₂SO₄, (ii) O₃, Et₂O, (iii) LiAlH₄

3: (i) Py, (ii) KOH, MeOH

4: Py

With pyridine; acetic acid;

DOI:10.1016/S0040-4020(01)91763-6

Reference yield:

Acetoxy-keton (30167-04-5) → Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester (30167-07-8)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) H₂SO₄, (ii) O₃, Et₂O, (iii) LiAlH₄

2: (i) Py, (ii) KOH, MeOH

3: Py

With pyridine;

DOI:10.1016/S0040-4020(01)91763-6

Reference yield:

(1S,2S,3S,6S)-3-(2-Hydroxy-ethyl)-2-(2-hydroxy-1-methyl-ethyl)-6-isopropyl-3-methyl-cyclohexanol (30167-06-7) → Acetic acid (1S,2S,3S,6S)-6-isopropyl-3-(2-methanesulfonyloxy-ethyl)-2-(2-methanesulfonyloxy-1-methyl-ethyl)-3-methyl-cyclohexyl ester (30167-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Py, (ii) KOH, MeOH

2: Py

With pyridine;

DOI:10.1016/S0040-4020(01)91763-6

upstream raw materials:

Acetic acid (1S,2S,3S,6S)-3-(2-hydroxy-ethyl)-2-(2-hydroxy-1-methyl-ethyl)-6-isopropyl-3-methyl-cyclohexyl ester

methanesulfonyl chloride

Acetic acid (1'S,4'aS,7'S,8'S,8'aR)-7'-isopropyl-1',4'a-dimethyl-octahydro-spiro[[1,3]dioxolane-2,2'-naphthalen]-8'-yl ester

Acetoxy-keton

Downstream raw materials:

6α-hydroxyelemol

(2S,3S,6S)-6-isopropyl-3-methyl-2-(prop-1-en-2-yl)-3-vinylcyclohexanone

Acetic acid (1S,2S,3S,6S)-2-isopropenyl-6-isopropyl-3-methyl-3-vinyl-cyclohexyl ester

Acetic acid (1S,2S,3S,6S)-3-(2-iodo-ethyl)-2-(2-iodo-1-methyl-ethyl)-6-isopropyl-3-methyl-cyclohexyl ester