(+/-)-dimethanothromboxane A₂

Base Information

Chemical Name:(+/-)-dimethanothromboxane A₂
CAS No.:73804-44-1
Molecular Formula:C₂₂H₃₆O₃
Molecular Weight:348.526
Hs Code.:

(+/-)-dimethanothromboxane A<sub>2</sub>

Synonyms:

Suppliers and Price of (+/-)-dimethanothromboxane A₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+/-)-dimethanothromboxane A₂

Chemical Property:

Purity/Quality:

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Technology Process of (+/-)-dimethanothromboxane A₂

There total 23 articles about (+/-)-dimethanothromboxane A₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 73509-45-2,73543-46-1,73837-11-3,74034-54-1,74034-55-2,84171-72-2
methyl (2R*,3S*)-(Z)-((E)-3-hydroxy-1-octenyl)bicyclo<3.1.1>heptane-2-hept-5-enoate

: 73509-46-3,73543-47-2,73804-44-1,74034-56-3,74034-57-4,84171-73-3
(+/-)-dimethanothromboxane A₂

Guidance literature:: With potassium hydroxide; In ethanol; at 45 ℃; for 0.833333h;
DOI:10.1016/S0040-4020(01)88648-8

Reference yield:

: 73509-45-2,73543-46-1,73837-11-3,74034-54-1,74034-55-2,84171-72-2
(Z)-7-[(2S,3R)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-bicyclo[3.1.1]hept-2-yl]-hept-5-enoic acid methyl ester

: 73509-46-3,73543-47-2,73804-44-1,74034-56-3,74034-57-4,84171-73-3
(Z)-7-[(2S,3R)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-bicyclo[3.1.1]hept-2-yl]-hept-5-enoic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 45 ℃; for 0.833333h;
DOI:10.1016/S0040-4020(01)88648-8

Reference yield:

: 35563-52-1
1-tributylphosphoranylidene-2-heptanone

: 73509-46-3,73543-47-2,73804-44-1,74034-56-3,74034-57-4,84171-73-3
(Z)-7-[(2S,3R)-3-((E)-(R)-3-Hydroxy-oct-1-enyl)-bicyclo[3.1.1]hept-2-yl]-hept-5-enoic acid

Guidance literature:: Multi-step reaction with 8 steps

1: 90 percent / diethyl ether / 24 h

2: 88 percent / NaBH₄ / methanol / 0.83 h / -40 °C

3: 94 percent / p-TsOH / CH₂Cl₂ / 0.33 h / 0 °C

4: DIBAL / toluene / 0.33 h / -50 °C

5: Et₃N, SO₃-pyridine / dimethylsulfoxide / 20 h

6: 1.) dimsylsodium / 1.) DMSO, 30 deg C, 1 h, 40 deg C, 1 h, 2.) ether

7: 32 percent / PPTS / methanol / 2 h / 55 °C

8: 5percent KOH / ethanol / 0.83 h / 45 °C

With potassium hydroxide; sodium tetrahydroborate; pyridine-SO₃ complex; dimsylsodium; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; toluene-4-sulfonic acid; triethylamine; In methanol; diethyl ether; ethanol; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1016/S0040-4020(01)88648-8