(R)-alpine borane

Base Information

• Chemical Name: (R)-alpine borane
• CAS No.: 100347-98-6
• Molecular Formula: C₁₈H₃₁B
• Molecular Weight: 258.255
• Mol file: 100347-98-6.mol

Synonyms:

Chemical Property of (R)-alpine borane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-alpine borane

There total 5 articles about (R)-alpine borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(+)-α-pinene (7785-70-8,25766-18-1) → (R)-alpine borane (73624-47-2,76695-88-0,100347-98-6,64106-79-2)

Guidance literature:

In tetrahydrofuran; at 24 ℃; for 24h; Product distribution; other time; hydroboration of 2-organylapopinenes with 9-borabicyclo<3.3.1>nonane; effect of steric factors of alkyl substituent on the rate of hydroboration; conversion;

DOI:10.1021/jo9617169

Reference yield:

(cyclopentadienyl)Fe(CO)2COPh + HB(C8H14)(C10H17)(1-) + lithium triethylborohydride (22560-16-3) → (R)-alpine borane (73624-47-2,76695-88-0,100347-98-6,64106-79-2)

Guidance literature:

In not given; byproducts: 1-phenylethanol; treatment of metal carbonyl with borohydride, then addn. of acetophenone, 2 h at -78°C, IR- and NMR-monitoring; quenching with water;

DOI:10.1016/S0020-1693(00)88992-6

Reference yield:

(CO)5MnC(O)CH2OCH3 + HB(C8H14)(C10H17)(1-) + lithium triethylborohydride (22560-16-3) → (R)-alpine borane (73624-47-2,76695-88-0,100347-98-6,64106-79-2)

Guidance literature:

In not given; byproducts: 1-phenylethanol; treatment of metal carbonyl with borohydride, then addn. of acetophenone, 2 h at -78°C, IR- and NMR-monitoring; quenching with water;

DOI:10.1016/S0020-1693(00)88992-6

upstream raw materials:

(+)-α-pinene

lithium triethylborohydride

dimanganese decacarbonyl

Refernces

• 1、 Dhokte, Ulhas P.,Brown, Herbert C.. "Hydroboration. 94. Rates of Hydroboration of 2-Organylapopinenes with 9-Borabicyclo[3.3.1]nonane, Providing B-(2-Organylapoisopinocampheyl)-9-borabicyclo[3.3.1]nonanes, Potentially Valuable for the Asymmetric Reduction of Prochiral Ketones". . p. 865 - 869. Retrieved 2007/10/03.