benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine

Base Information

• Chemical Name: benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine
• CAS No.: 118722-35-3
• Molecular Formula: C₂₆H₂₈N₄O₈
• Molecular Weight: 524.53

Synonyms:

Chemical Property of benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine

There total 3 articles about benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

benzyl ester of N-tert-butoxycarbonylasparaginylglycine (76626-66-9) + benzyloxycarbonylpyroglutamic acid pentafluorophenyl ester (78148-14-8) → benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine (118722-35-3)

Guidance literature:

DOI:10.1007/BF00596754

Reference yield:

N-(tert-butyloxycarbonyl)-L-asparagine p-nitrophenyl ester (4587-33-1) → benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine (118722-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent

2: 55 percent

DOI:10.1007/BF00596754

Reference yield:

Gly-OBz (1738-68-7) → benzyl ester of N-benzyloxycarbonylpyroglutamylasparaginylglycine (118722-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent

2: 55 percent

DOI:10.1007/BF00596754

upstream raw materials:

benzyl ester of N-tert-butoxycarbonylasparaginylglycine

benzyloxycarbonylpyroglutamic acid pentafluorophenyl ester

N-(tert-butyloxycarbonyl)-L-asparagine p-nitrophenyl ester

Gly-OBz

Downstream raw materials:

pyroglutamylasparaginylglycine

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