4-HEPTYLANILINE

Base Information

• Chemical Name: 4-HEPTYLANILINE
• CAS No.: 37529-27-4
• Molecular Formula: C13H21 N
• Molecular Weight: 191.316
• Hs Code.: 29214990
• Mol file: 37529-27-4.mol

Synonyms:Aniline,p-heptyl- (6CI,7CI); 4-Heptylaniline; 4-Heptylphenylamine; 4-n-Heptylaniline;p-Heptylaniline; p-n-Heptylaniline

Chemical Property of 4-HEPTYLANILINE

Chemical Property:

• Appearance/Colour: Light yellow to light tan liquid, aromatic amine odor
• Vapor Pressure: 0.00327mmHg at 25°C
• Melting Point: 75-76 °C
• Refractive Index: n20/D 1.52(lit.)
• Boiling Point: 159 °C18 mm Hg(lit.)
• PKA: 4.97±0.10(Predicted)
• Flash Point: >230 °F
• PSA: 26.02000
• Density: 0.91 g/mL at 25 °C(lit.)
• LogP: 4.36290
• Sensitive.: Light Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Heptylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-HEPTYLANILINE

There total 28 articles about 4-HEPTYLANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-(4-nitrophenyl)-7-phenylthioheptane (257289-12-6) → 4-heptylaniline (37529-27-4) + 1-(4-aminophenyl)-7-phenylthioheptane (257289-15-9)

Guidance literature:

With hydrazine hydrate; nickel; In methanol; for 3h; Heating;

DOI:10.1021/jo991139z

Reference yield: 75.0%

1-(2-bromo-4-nitrophenyl)heptyne (121866-20-4) → 4-heptylaniline (37529-27-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jo00279a040

Reference yield:

7-(4-nitrophenyl)heptane (192934-88-6) → 4-heptylaniline (37529-27-4)

Guidance literature:

With hydrogen; platinum on activated charcoal; In methanol;

DOI:10.1021/jm970232h

upstream raw materials:

1-(4-heptyl-phenyl)-ethanone oxime

n-heptan1ol

aniline

1-(2-bromo-4-nitrophenyl)heptyne

Downstream raw materials:

N-(4-heptyl-phenyl)-glycine ethyl ester

5-Ethoxy-2-{[(E)-4-heptyl-phenylimino]-methyl}-phenol

p-ethoxybenzylidene p-heptylaniline

(2R,3S,4R,5R)-2-[(4-Heptyl-phenylamino)-methyl]-tetrahydro-pyran-2,3,4,5-tetraol

Refernces

• 1、 Zygadlo,Dardas,Nowicka,Hofmann,Galewski. "Liquid-crystalline polymorphism of symmetrical azobananas: Bis(4-(4-alkylphenyl)azophenyl) 2-nitroisophtalates". . p. 283 - 291. Retrieved 2011/08/02.
• 2、 Gamage, Swarna A.,Figgitt, David P.,Wojcik, Stanley J.,Ralph, Raymond K.,Ransijn, Adriana,Mauel, Jacques,Yardley, Vanessa,Snowdon, Diane,Croft, Simon L.,Denny, William A.. "Structure-activity relationships for the antileishmanial and antitrypanosomal activities of 1'-substituted 9-anilinoacridines". . p. 2634 - 2642. Retrieved 2007/10/03.