(+/-)-laurenene

Base Information

• Chemical Name: (+/-)-laurenene
• CAS No.: 119181-34-9
• Molecular Formula: C₂₀H₃₂
• Molecular Weight: 272.474
• Mol file: 119181-34-9.mol

Synonyms:

Chemical Property of (+/-)-laurenene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-laurenene

There total 40 articles about (+/-)-laurenene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

C28H54N4O4P2 → (+/-)-laurenene (72779-23-8,90025-15-3,110455-92-0,119181-34-9)

Guidance literature:

With lithium; ethylamine;

DOI:10.1021/ja00222a072

Reference yield:

C17H26O2 → (+/-)-laurenene (72779-23-8,90025-15-3,110455-92-0,119181-34-9)

Guidance literature:

Multi-step reaction with 11 steps

1: (COCl)2, Et₃N, DMSO / CH₂Cl₂ / -78 °C

2: CH₂Cl₂ / 0.5 h / 40 °C

3: Na, NH₃ / diethyl ether / 0.08 h / -33 °C

4: H₂ / Pd/C / ethanol

5: LiALH₄ / diethyl ether / 25 °C

6: (COCl)2, Et₃N, DMSO / CH₂Cl₂ / -78 °C

7: p-TSOH / benzene / 3 h / 80 °C

8: NaBH₄, CeCl₃ / methanol

9: 1.) KH, 2.) BuLi / 1.) THF, 2.) hexane, 0 deg C

10: pyridine

11: LiEt₃BH / tetrahydrofuran

With pyridine; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; cerium(III) chloride; oxalyl dichloride; ammonia; hydrogen; sodium; potassium hydride; lithium triethylborohydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; benzene;

DOI:10.1021/ja00254a058

Reference yield:

C17H24O2 → (+/-)-laurenene (72779-23-8,90025-15-3,110455-92-0,119181-34-9)

Guidance literature:

Multi-step reaction with 10 steps

1: CH₂Cl₂ / 0.5 h / 40 °C

2: Na, NH₃ / diethyl ether / 0.08 h / -33 °C

3: H₂ / Pd/C / ethanol

4: LiALH₄ / diethyl ether / 25 °C

5: (COCl)2, Et₃N, DMSO / CH₂Cl₂ / -78 °C

6: p-TSOH / benzene / 3 h / 80 °C

7: NaBH₄, CeCl₃ / methanol

8: 1.) KH, 2.) BuLi / 1.) THF, 2.) hexane, 0 deg C

9: pyridine

10: LiEt₃BH / tetrahydrofuran

With pyridine; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; cerium(III) chloride; oxalyl dichloride; ammonia; hydrogen; sodium; potassium hydride; lithium triethylborohydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; benzene;

DOI:10.1021/ja00254a058

upstream raw materials:

laurenan-2β-ol

laurenan-2α-yl acetate

laurenan-2β-yl acetate

laurenan-2α-ol