(+/-)11(12)-EPETRE METHYL ESTER

Base Information

• Chemical Name: (+/-)11(12)-EPETRE METHYL ESTER
• CAS No.: 73799-06-1
• Molecular Formula: C₂₁H₃₄O₃
• Molecular Weight: 334.499
• Mol file: 73799-06-1.mol

Synonyms:

Chemical Property of (+/-)11(12)-EPETRE METHYL ESTER

Chemical Property:

Purity/Quality:

≥98% ^*data from raw suppliers

(+/-)11(12)-EPETRE METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)11(12)-EPETRE METHYL ESTER

There total 2 articles about (+/-)11(12)-EPETRE METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

14,15-Epoxyeicosatrienoic acid methylester (197508-63-7) → (5Z,8Z)-10-[((E)-3-Oct-2-enyl)-oxiranyl]-deca-5,8-dienoic acid methyl ester (73799-06-1,90080-08-3,90693-45-1,98974-57-3,110901-54-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) KBr, 2.) t-BuOOH, vanadyl acetylacetonate / 1.) AcOH-H₂O-THF, 5 deg C, 12 h, 2.) benzene, 23 deg C, 130 min

2: 1.) trifluorometanesulphonic anhydride - pyridine, 2.) hexamethylphosphorous triamide / 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) 0 deg C, 30 min

With pyridine; tert.-butylhydroperoxide; trifluoromethylsulfonic anhydride; vanadyl acetylacetonate; potassium bromide; Hexamethylphosphorous triamide;

DOI:10.1021/ja00524a043

Reference yield:

(5Z,8Z)-10-[3-((2S,3S)-3-Bromo-2-hydroxy-octyl)-oxiranyl]-deca-5,8-dienoic acid methyl ester (73799-05-0) → cis-11,12-epoxyeicosatrienoic acid methyl ester (331965-16-3) + (5Z,8Z)-10-[((E)-3-Oct-2-enyl)-oxiranyl]-deca-5,8-dienoic acid methyl ester (73799-06-1,90080-08-3,90693-45-1,98974-57-3,110901-54-7)

Guidance literature:

With pyridine; trifluoromethylsulfonic anhydride; Hexamethylphosphorous triamide; Yield given. Multistep reaction. Yields of byproduct given; 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) 0 deg C, 30 min;

DOI:10.1021/ja00524a043

upstream raw materials:

(5Z,8Z)-10-[3-((2S,3S)-3-Bromo-2-hydroxy-octyl)-oxiranyl]-deca-5,8-dienoic acid methyl ester

14,15-Epoxyeicosatrienoic acid methylester