3',5'-di-O-benzoyl-2'-deoxy-L-N⁶-benzoyladenosine

Base Information

• Chemical Name: 3',5'-di-O-benzoyl-2'-deoxy-L-N⁶-benzoyladenosine
• CAS No.: 137157-38-1
• Molecular Formula: C₃₁H₂₅N₅O₆
• Molecular Weight: 563.569
• Mol file: 137157-38-1.mol

Synonyms:

Chemical Property of 3',5'-di-O-benzoyl-2'-deoxy-L-N⁶-benzoyladenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3',5'-di-O-benzoyl-2'-deoxy-L-N⁶-benzoyladenosine

There total 1 articles about 3',5'-di-O-benzoyl-2'-deoxy-L-N⁶-benzoyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzoyladenine (4005-49-6) + 3',5'-dibenzoyl-2'-deoxy-β-L-uridine (31615-99-3) → C31H25N5O6 (137157-37-0) + 3',5'-di-O-benzoyl-2'-deoxy-L-N6-benzoyladenosine (137157-38-1)

Guidance literature:

With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate; Yield given. Multistep reaction. Yields of byproduct given; 1.) 1,2-dichloroethane, reflux, 30 min, 2.) 1,2-dichloroethane, reflux, 4 h;

DOI:10.1021/jm00100a029

Reference yield: 69.0%

3',5'-di-O-benzoyl-2'-deoxy-L-N6-benzoyladenosine (137157-38-1) → L-dA (14365-45-8,7005-15-4)

Guidance literature:

With pyridine; ammonium hydroxide; at 50 ℃; for 24h;

DOI:10.1021/jm00100a029

upstream raw materials:

N-benzoyladenine

3',5'-dibenzoyl-2'-deoxy-β-L-uridine

Downstream raw materials:

L-dA