10-Oxocodeine 6-Acetate

Base Information

• Chemical Name: 10-Oxocodeine 6-Acetate
• CAS No.: 96562-83-3
• Molecular Formula: C₂₀H₂₁NO₅
• Molecular Weight: 355.39
• Mol file: 96562-83-3.mol

Synonyms:

Chemical Property of 10-Oxocodeine 6-Acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 10-Oxocodeine 6-Acetate

There total 3 articles about 10-Oxocodeine 6-Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-acetylcodeine (6703-27-1) → 6-Acetyl-10-oxocodeine (96562-83-3) + 6-Acetyl-10-hydroxycodeine (96562-81-1)

Guidance literature:

With potassium dichromate; sulfuric acid; In water; at 5 ℃; for 3h;

Reference yield:

6-Acetyl-10-hydroxycodeine (96562-81-1) → 6-Acetyl-10-oxocodeine (96562-83-3)

Guidance literature:

With manganese(IV) oxide; In chloroform; for 17h;

Reference yield:

6-acetylcodeine (6703-27-1) → 6-Acetyl-10-oxocodeine (96562-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 549 mg / K₂Cr₂O₇, H₂SO₄ / H₂O / 3 h / 5 °C

2: 210 mg / MnO₂ / CHCl₃ / 17 h

With potassium dichromate; manganese(IV) oxide; sulfuric acid; In chloroform; water;

upstream raw materials:

6-Acetyl-10-hydroxycodeine

6-acetylcodeine

Downstream raw materials:

10-Oxomorphine

Refernces