4,4-dimethyl-2,2-diphenyltetrahydrofuran

Base Information

• Chemical Name: 4,4-dimethyl-2,2-diphenyltetrahydrofuran
• CAS No.: 82668-87-9
• Molecular Formula: C₁₈H₂₀O
• Molecular Weight: 252.356
• Mol file: 82668-87-9.mol

Synonyms:

Chemical Property of 4,4-dimethyl-2,2-diphenyltetrahydrofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4-dimethyl-2,2-diphenyltetrahydrofuran

There total 3 articles about 4,4-dimethyl-2,2-diphenyltetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dibromo-1,1-diphenylethane (40957-21-9) → 4,4-dimethyl-2,2-diphenyltetrahydrofuran (82668-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / 1 h / 0 °C

2: Bu₃SnH

With potassium hydroxide; tri-n-butyl-tin hydride;

DOI:10.1246/bcsj.55.1498

Reference yield:

2-(2-methyl-2-propenyloxy)-2,2-diphenylethyl bromide (74249-44-8) → 4,4-dimethyl-2,2-diphenyltetrahydrofuran (82668-87-9)

Guidance literature:

With bis(dimethylglyoximato)pyridinecobaltate(I) ion; Yield given. Multistep reaction; 1.) MeOH, RT, 6 h, 2.) CHCl₃, irradiation;

DOI:10.1246/bcsj.55.1498

Reference yield:

2-(2-methyl-2-propenyloxy)-2,2-diphenylethyl bromide (74249-44-8) → 1-(2-methyl-2-propenyloxy)-1,1-diphenylethane + 4,4-dimethyl-2,2-diphenyltetrahydrofuran (82668-87-9)

Guidance literature:

With tri-n-butyl-tin hydride;

DOI:10.1246/bcsj.55.1498

upstream raw materials:

2-(2-methyl-2-propenyloxy)-2,2-diphenylethyl bromide

1,2-dibromo-1,1-diphenylethane