(S)-bambuterol hydrochloride

Base Information

• Chemical Name: (S)-bambuterol hydrochloride
• CAS No.: 1020652-57-6
• Molecular Formula: C₁₈H₂₉N₃O₅*ClH
• Molecular Weight: 403.906

Synonyms:

Chemical Property of (S)-bambuterol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-bambuterol hydrochloride

There total 3 articles about (S)-bambuterol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Bambuterol hydrochloride (81732-46-9) → (S)-bambuterol hydrochloride (1020652-57-6,81732-46-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / water / 0.5 h

2.1: ethyl acetate / 2 h / 50 - 60 °C / Green chemistry

3.1: potassium carbonate / water / 0.5 h

3.2: 1 h / pH 1 / Cooling with ice

With potassium carbonate; In water; ethyl acetate;

DOI:10.1002/chir.22573

Reference yield:

bambuterol → (S)-bambuterol hydrochloride (1020652-57-6,81732-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethyl acetate / 2 h / 50 - 60 °C / Green chemistry

2.1: potassium carbonate / water / 0.5 h

2.2: 1 h / pH 1 / Cooling with ice

With potassium carbonate; In water; ethyl acetate;

DOI:10.1002/chir.22573

Reference yield:

(S)-bambuterol (S)-o-chloromandelic acid → (S)-bambuterol hydrochloride (1020652-57-6,81732-46-9)

Guidance literature:

(S)-bambuterol (S)-o-chloromandelic acid; With potassium carbonate; In water; for 0.5h;

With hydrogenchloride; In ethanol; water; for 1h; pH=1; Cooling with ice;

DOI:10.1002/chir.22573

upstream raw materials:

Bambuterol hydrochloride

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