5-(Carboxyhydroxymethyl)uridine

Base Information

Chemical Name:5-(Carboxyhydroxymethyl)uridine
CAS No.:934743-11-0
Molecular Formula:C₁₁H₁₄N₂O₉
Molecular Weight:318.24
Hs Code.:
DSSTox Substance ID:DTXSID401131492
Metabolomics Workbench ID:53765
Wikidata:Q27109309

Synonyms:5-(carboxyhydroxymethyl)uridine

Suppliers and Price of 5-(Carboxyhydroxymethyl)uridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 5-(Carboxyhydroxymethyl)uridine

Chemical Property:

XLogP3:-2.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:318.06993003
Heavy Atom Count:22
Complexity:534

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)C(C(=O)O)O
Isomeric SMILES:C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(C(=O)O)O
Uses 5-Carboxyhydroxymethyluridine is a naturally occuring modified nucleoside in RNA that assists in RNA stability, folding and other functions.

Technology Process of 5-(Carboxyhydroxymethyl)uridine

There total 4 articles about 5-(Carboxyhydroxymethyl)uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: C₁₃H₁₄N₂O₁₀

: 934743-11-0
5-carboxyhydroxymethyluridine

Guidance literature:: With trifluoroacetic acid; In water; at 60 ℃; for 15h;
DOI:10.1039/c9ra08548c

Reference yield:

: 2',3',5'-tri-O-acetyl-N³-benzoyluridine-5-malonic acid diethyl ester

: 934743-11-0
5-carboxyhydroxymethyluridine

Guidance literature:: Multi-step reaction with 3 steps

1: selenium(IV) oxide / 1,4-dioxane / 18 h / Reflux

2: methanol / 20 h / 20 °C

3: trifluoroacetic acid / water / 15 h / 60 °C

With selenium(IV) oxide; trifluoroacetic acid; In 1,4-dioxane; methanol; water;
DOI:10.1039/c9ra08548c

Reference yield:

: 2',3',5'-tri-O-acetyl-N³-benzoyluridine-5-α-hydroxymalonic acid diethyl ester

: 934743-11-0
5-carboxyhydroxymethyluridine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 20 h / 20 °C

2: trifluoroacetic acid / water / 15 h / 60 °C

With trifluoroacetic acid; In methanol; water;
DOI:10.1039/c9ra08548c