4-fluoro-3,5-dimethylbenzoyl chloride

Base Information

• Chemical Name: 4-fluoro-3,5-dimethylbenzoyl chloride
• CAS No.: 886501-66-2
• Molecular Formula: C₉H₈ClFO
• Molecular Weight: 186.613
• Hs Code.: 2916399090
• Mol file: 886501-66-2.mol

Synonyms:

Chemical Property of 4-fluoro-3,5-dimethylbenzoyl chloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-Fluoro-3,5-dimethylbenzoyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-fluoro-3,5-dimethylbenzoyl chloride

There total 1 articles about 4-fluoro-3,5-dimethylbenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluoro-3,5-dimethylbenzoic acid (120512-59-6) → 4-fluoro-3,5-dimethylbenzoyl chloride (886501-66-2)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; Inert atmosphere;

Reference yield:

4-fluoro-3,5-dimethylbenzoyl chloride (886501-66-2) + 2-(4-isopropylphenyl)ethanamine hydrochloride (61035-87-8) → 4-fluoro-N-(4-isopropylphenylethyl)-3,5-dimethylbenzamide

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere; Cooling with ice;

Reference yield:

4-fluoro-3,5-dimethylbenzoyl chloride (886501-66-2) → 1-(4-fluoro-3,5-dimethylphenyl)-7-isopropyl-3,4-dihydroisoquinoline

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 12 h / 20 °C / Inert atmosphere; Cooling with ice

2: phosphorus pentoxide; trichlorophosphate / 5,5-dimethyl-1,3-cyclohexadiene / 3 h / Inert atmosphere; Reflux

With pyridine; phosphorus pentoxide; trichlorophosphate; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane;

upstream raw materials:

4-fluoro-3,5-dimethylbenzoic acid