monacolin K (hydroxy acid form)

Base Information

• Chemical Name: monacolin K (hydroxy acid form)
• CAS No.: 759417-05-5
• Molecular Formula: C₂₄H₃₈O₆
• Molecular Weight: 422.562
• Mol file: 759417-05-5.mol

Synonyms:

Chemical Property of monacolin K (hydroxy acid form)

Chemical Property:

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Technology Process of monacolin K (hydroxy acid form)

There total 1 articles about monacolin K (hydroxy acid form) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Sodium; (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-((R)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-3,5-dihydroxy-heptanoate (101400-30-0) → monacolin K (hydroxy acid form) (759417-05-5,76556-02-0,77285-87-1)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1021/jm00155a040

upstream raw materials:

Sodium; (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-((R)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-3,5-dihydroxy-heptanoate

Refernces