4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide

Base Information

Chemical Name:4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide
CAS No.:892711-75-0
Molecular Formula:C₂₀H₂₀N₂O₂
Molecular Weight:320.391
Hs Code.:

Synonyms:

Suppliers and Price of 4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
25mg
$ 460.00

Tocris
CDN1163 ≥98%(HPLC)
50
$ 670.00

Tocris
CDN1163 ≥98%(HPLC)
10
$ 162.00

DC Chemicals
CDN1163 >98%
100 mg
$ 550.00

DC Chemicals
CDN1163 >98%
1 g
$ 1900.00

Crysdot
4-Isopropoxy-N-(2-methylquinolin-8-yl)benzamide 97%
1g
$ 1836.00

ChemScene
CDN1163 99.72%
100mg
$ 640.00

ChemScene
CDN1163 99.72%
5mg
$ 70.00

ChemScene
CDN1163 99.72%
10mg
$ 110.00

ChemScene
CDN1163 99.72%
50mg
$ 360.00

Total 14 raw suppliers

Chemical Property of 4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide

Chemical Property:

Melting Point:87 - 89°C

Purity/Quality:

99%, ^*data from raw suppliers

4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description CDN1163 (892711-75-0) is an allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).1,2? It lowered fasting glucose levels, improved glucose tolerance, and ameliorated hepatitis steatosis in ob/ob mice.1?? CDN1163 also rescued neurons from ER-stress-induced cell death in vitro and displayed significant efficacy in a rat 6-hydroxydopamine (6-OHDA) model of Parkinson’s disease.2 It reduced age-related muscle atrophy and weakness in a C57BL/6J mice.3? CDN1163 decreased inflammatory cytokines and chemokines and attenuated mitochondrial dysfunction in Influenza A infected H1395 cells.4
Uses 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide is an allosteric activator that increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes. 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide may have therapeutic potential for treating type-2 diabetes and metabolic dysfunction.

Technology Process of 4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide

There total 1 articles about 4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18978-78-4
2-methyl-8-aminoquinoline

: 13205-46-4
4-isopropoxybenzoic acid

: 892711-75-0
4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide

Guidance literature:: 4-isopropoxybenzoic acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.166667h;

2-methyl-8-aminoquinoline; In N,N-dimethyl-formamide; for 20h;