tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate

Base Information

Chemical Name:tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate
CAS No.:943325-32-4
Molecular Formula:C₁₃H₁₉FN₂O₂
Molecular Weight:254.304
Hs Code.:
Mol file:943325-32-4.mol

Synonyms:

Suppliers and Price of tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-[2-AMINO-1-(3-FLUOROPHENYL)ETHYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00%
5MG
$ 497.06

Total 0 raw suppliers

Chemical Property of tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate

Chemical Property:

Purity/Quality:: N-[2-AMINO-1-(3-FLUOROPHENYL)ETHYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate

There total 6 articles about tert-butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 926292-12-8,943325-32-4
[(R)-2-amino-1-(3-fluoro-phenyl)-ethyl]-carbamic acid tert-butyl ester

Guidance literature:

Reference yield:

: C₁₃H₁₇FN₄O₂

: 943325-32-4
C₁₃H₁₉FN₂O₂

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃;
DOI:10.1021/acs.jmedchem.7b01861

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 943325-32-4
C₁₃H₁₉FN₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: triethylamine / dichloromethane / 0.5 h / 0 °C

3: sodium azide / N,N-dimethyl-formamide / 60 °C

4: hydrogen; palladium on activated charcoal / ethanol / 20 °C

With sodium azide; palladium on activated charcoal; hydrogen; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b01861