ADX 10059 hydrochloride

Base Information

Chemical Name:ADX 10059 hydrochloride
CAS No.:757949-98-7
Molecular Formula:C₁₅H₁₃FN₂*ClH
Molecular Weight:276.741
Hs Code.:
Mol file:757949-98-7.mol

Synonyms:

Suppliers and Price of ADX 10059 hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
ADX 10059 hydrochloride
10mg
$ 466.00

TRC
ADX10059Hydrochloride
2.5mg
$ 250.00

Tocris
ADX10059hydrochloride ≥99%(HPLC)
50
$ 762.00

Tocris
ADX10059hydrochloride ≥99%(HPLC)
10
$ 189.00

ApexBio Technology
ADX10059hydrochloride
10mg
$ 322.00

ApexBio Technology
ADX10059hydrochloride
50mg
$ 1305.00

American Custom Chemicals Corporation
ADX-10059 HYDROCHLORIDE 99.00%
5MG
$ 497.00

Total 8 raw suppliers

Chemical Property of ADX 10059 hydrochloride

Chemical Property:

Solubility.:<6.92mg/ml in H2O; <27.67mg/ml in DMSO

Purity/Quality:

≥99% by HPLC ^*data from raw suppliers

ADX 10059 hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses ADX 10059 Hydrochloride is used in the synthetic preparation of novel 2-(hetero)arylalkynylpyridin-3-amines as mGluR5 antagonists.

Technology Process of ADX 10059 hydrochloride

There total 3 articles about ADX 10059 hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 757949-98-7
Raseglurant hydrochloride

Guidance literature:

Reference yield:

: 2-((3-fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine

: 757949-98-7
Raseglurant hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; water;
DOI:10.7554/eLife.23545

Reference yield:

: 104829-98-3
3-amino-2-bromo-4,6-dimethylpyridine

: 757949-98-7
Raseglurant hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 8 h / 40 °C / Inert atmosphere

2: hydrogenchloride / diethyl ether; water

With hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In diethyl ether; water; N,N-dimethyl-formamide;
DOI:10.7554/eLife.23545