Technology Process of 11-(3-dimethylaminopropyl)-11H-dibenzo-1,4-dithiepin
There total 9 articles about 11-(3-dimethylaminopropyl)-11H-dibenzo-1,4-dithiepin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: KOH / ethanol / 6 h / Heating
2: 60 percent / triphenylphosphine, H2O / dioxane / 1 h / 40 °C
3: 17 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
4: 1) n-butyllithium / 1) ether/hexane, 30 min
With
potassium hydroxide; n-butyllithium; water; copper; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072
- Guidance literature:
-
Multi-step reaction with 4 steps
1: KOH / ethanol / 6 h / Heating
2: 60 percent / triphenylphosphine, H2O / dioxane / 1 h / 40 °C
3: 17 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
4: 1) n-butyllithium / 1) ether/hexane, 30 min
With
potassium hydroxide; n-butyllithium; water; copper; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072
- Guidance literature:
-
Multi-step reaction with 5 steps
1: chlorosulfonic acid / CHCl3 / 1) 3 h room temperature 2) 2 h reflux
2: Zn, hydrochloric acid / dioxane / 1.5 h / 80 - 90 °C
3: liquid ammonia, Na / liquid ammonia / 0.67 h
4: 54 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
5: 1) n-butyllithium / 1) ether/hexane, 30 min
With
hydrogenchloride; chlorosulfonic acid; n-butyllithium; ammonia; sodium; copper; potassium carbonate; zinc;
In
1,4-dioxane; chloroform; ammonia; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072