Technology Process of 11-(3-dimethylaminopropyl)-11H-dibenzo-1,4-dithiepin
There total 9 articles about 11-(3-dimethylaminopropyl)-11H-dibenzo-1,4-dithiepin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: KOH / ethanol / 6 h / Heating
2: 60 percent / triphenylphosphine, H2O / dioxane / 1 h / 40 °C
3: 17 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
4: 1) n-butyllithium / 1) ether/hexane, 30 min
With
potassium hydroxide; n-butyllithium; water; copper; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072
- Guidance literature:
-
Multi-step reaction with 4 steps
1: KOH / ethanol / 6 h / Heating
2: 60 percent / triphenylphosphine, H2O / dioxane / 1 h / 40 °C
3: 17 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
4: 1) n-butyllithium / 1) ether/hexane, 30 min
With
potassium hydroxide; n-butyllithium; water; copper; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072
- Guidance literature:
-
Multi-step reaction with 5 steps
1: chlorosulfonic acid / CHCl3 / 1) 3 h room temperature 2) 2 h reflux
2: Zn, hydrochloric acid / dioxane / 1.5 h / 80 - 90 °C
3: liquid ammonia, Na / liquid ammonia / 0.67 h
4: 54 percent / K2CO3, Cu / dimethylformamide / 6 h / Heating
5: 1) n-butyllithium / 1) ether/hexane, 30 min
With
hydrogenchloride; chlorosulfonic acid; n-butyllithium; ammonia; sodium; copper; potassium carbonate; zinc;
In
1,4-dioxane; chloroform; ammonia; N,N-dimethyl-formamide;
DOI:10.1135/cccc19820072
