2-{[(2-methoxyethyl)amino]methyl}phenol

Base Information

• Chemical Name: 2-{[(2-methoxyethyl)amino]methyl}phenol
• CAS No.: 827328-20-1
• Molecular Formula: C₁₀H₁₅NO₂
• Molecular Weight: 181.235
• Mol file: 827328-20-1.mol

Synonyms:

Chemical Property of 2-{[(2-methoxyethyl)amino]methyl}phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{[(2-methoxyethyl)amino]methyl}phenol

There total 2 articles about 2-{[(2-methoxyethyl)amino]methyl}phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-(((2-methoxyethyl)imino)methyl)phenol) → 2-{[(2-methoxyethyl)amino]methyl}phenol (827328-20-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;

DOI:10.1016/j.molstruc.2016.03.085

Reference yield:

salicylaldehyde (90-02-8) → 2-{[(2-methoxyethyl)amino]methyl}phenol (827328-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 1 h / Reflux

2: sodium tetrahydroborate / methanol / 2 h / 20 °C

With sodium tetrahydroborate; In methanol;

DOI:10.1016/j.molstruc.2016.03.085

upstream raw materials:

salicylaldehyde

Refernces

Structural and computational characterization of 4′,4′,6′,6′-tetrachloro-3-(2-methoxyethyl)-3H,4H-spiro-1,3,2-benzoxaza phosphinine-2,2′- [1,3,5,2,4,6] triazatriphosphinine

10.1016/j.molstruc.2016.03.085

The study presents the synthesis and characterization of a novel monospirocyclic phosphazene derivative, 4',4',6',6'-tetrachloro-3-(2-methoxyethyl)-3H,4H-spiro-1,3,2-benzoxaza phosphinine-2,2'-[1,3,5,2,4,6]triazatriphosphinine (SP1). The compound was synthesized by reacting hexachlorocyclotriphosphazene (N3P3Cl6) with the N/O donor-type molecule 2-{[(2-methoxyethyl)amino]methyl}phenol. The synthesized SP1 was characterized using various analytical techniques, including elemental analyses, mass spectrometry (MS), Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR) spectroscopy, and single-crystal X-ray diffraction analysis. The purpose of these chemicals and techniques was to verify the structure and investigate the properties of the newly synthesized compound. The study also employed density functional theory (DFT) calculations using the B3LYP method with a 6-311++G(d,p) basis set to predict the electrophilic and nucleophilic attack centers in SP1, further understanding its reactivity and potential applications in areas such as biomaterials, protective coatings, drug delivery, and fire-resistant materials.