3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Base Information

Chemical Name:3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid
CAS No.:777857-43-9
Molecular Formula:C₁₉H₂₀O₅
Molecular Weight:328.365
Hs Code.:
DSSTox Substance ID:DTXSID001132286
ChEMBL ID:CHEMBL1423133
Mol file:777857-43-9.mol

Synonyms:777857-43-9;3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid;3-(3-tert-butyl-5-methyl-7-oxofuro[3,2-g]chromen-6-yl)propanoic acid;3-(3-(tert-Butyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid;MFCD03851970;3-{3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl}propanoic acid;ChemDiv3_014630;MLS000778352;CHEMBL1423133;DTXSID001132286;HMS1514I22;HMS2757A17;CGB85743;BBL030160;STK713391;3-(3-tert-Butyl-5-methyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)propanoic acid;AKOS001893137;IDI1_030428;SMR000415146;VS-09646;EN300-303061;3-(1,1-Dimethylethyl)-5-methyl-7-oxo-7H-furo[3,2-g][1]benzopyran-6-propanoic acid;3-(3-(tert-Butyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoicacid;3-(3-tert-Butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-propionic acid

Suppliers and Price of 3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(3-tert-Butyl-5-methyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)propanoic acid
500mg
$ 119.00

Crysdot
3-(3-(tert-Butyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoicacid 97%
5g
$ 349.00

Total 4 raw suppliers

Chemical Property of 3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:328.13107373
Heavy Atom Count:24
Complexity:571

Purity/Quality:

98%min ^*data from raw suppliers

3-(3-tert-Butyl-5-methyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)propanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=O)OC2=CC3=C(C=C12)C(=CO3)C(C)(C)C)CCC(=O)O

Technology Process of 3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

There total 5 articles about 3-(3-tert-butyl-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 670244-18-5
ethyl 3-[7'-(3'',3''-dimethyl-2''-oxobutoxy)-4'-methyl-2'-oxochromen-3'-yl]propanoate

: 777857-43-9
(3'-tert-butyl-5'-methyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)propionic acid

Guidance literature:: With sodium hydroxide; Heating;
DOI:10.1023/B:RUBI.0000030137.88504.10

Reference yield:

: 1501-06-0
diethyl 2-acetylglutarate

: 777857-43-9
(3'-tert-butyl-5'-methyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / HCl / ethanol / 20 °C

2: 77 percent / Na₂CO₃ / acetone / 50 - 56 °C

3: 81 percent / NaOH / Heating

With hydrogenchloride; sodium hydroxide; sodium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/B:RUBI.0000030137.88504.10

Reference yield:

: 5969-19-7
3-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)propionic acid ethyl ester

: 777857-43-9
(3'-tert-butyl-5'-methyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / Na₂CO₃ / acetone / 50 - 56 °C

2: 81 percent / NaOH / Heating

With sodium hydroxide; sodium carbonate; In acetone; 1: Williamson reaction;
DOI:10.1023/B:RUBI.0000030137.88504.10