(1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid

Base Information

Chemical Name:(1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid
CAS No.:852679-66-4
Molecular Formula:C₉H₁₃NO₄
Molecular Weight:199.207
Hs Code.:

Synonyms:

Suppliers and Price of (1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(±)-LY395756
1mg
$ 180.00

ApexBio Technology
(±)-LY395756
10mg
$ 448.00

ApexBio Technology
(±)-LY395756
50mg
$ 1851.00

American Custom Chemicals Corporation
LY 395756 95.00%
5MG
$ 496.65

Total 5 raw suppliers

Chemical Property of (1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid

Chemical Property:

Storage Temp.:Store at +4°C

Purity/Quality:

≥98% by HPLC ^*data from raw suppliers

(±)-LY395756 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (±)-LY 395756 is an agonist at mGlu2 receptors and an antagonist at mGlu3 receptors.

Technology Process of (1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid

There total 17 articles about (1S,2S,4R,5R,6S)-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1359762-15-4
di-tert-butyl (1S,2S,4R,5R,6S)-2-tert-butoxycarbonylamino-4-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylate

: 852679-76-6,852679-66-4,191399-35-6
1S,2S,4R,5R,6S-2-amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylate

Guidance literature:: With acetic acid; In water; at 160 ℃; for 0.0833333h; Microwave irradiation;
DOI:10.1016/j.tetlet.2012.01.033

Reference yield: 78.0%

: (-)-ethyl-2-spiro-5-hydantoin-4-methylbicyclo[3.1.0]hexane 6-carboxylate

: 852679-66-4,191399-35-6
(-)-2-amino-4-methylbicyclo[3.1.0]hexane 2,6-dicarboxylic acid

Guidance literature:: With sodium hydroxide; for 24h; Heating;
DOI:10.1021/jm040222y

Reference yield: 77.0%

: 1379471-57-4
di-tert-butyl (1S,2S,4S,5R,6S)-2-tert-butoxycarbonylamino-4-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylate

: 1379471-55-2,852679-66-4,191399-35-6
(1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Guidance literature:: di-tert-butyl (1S,2S,4S,5R,6S)-2-tert-butoxycarbonylamino-4-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylate; With methanesulfonic acid; In water; acetone; at 60 ℃; for 16h;

With sodium hydroxide; pH=2;

DOI:10.1021/ol300516y