Foxy-5

Base Information

• Chemical Name: Foxy-5
• CAS No.: 881188-51-8
• Molecular Formula: C₂₆H₄₂N₆O₁₂S₂
• Molecular Weight: 694.784

Synonyms:

Chemical Property of Foxy-5

Chemical Property:

• Boiling Point: 1244.1±65.0 °C(Predicted)
• Density: 1.368±0.06 g/cm3(Predicted)

Purity/Quality:

≥98% ^*data from raw suppliers

Foxy 5 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Foxy 5 is a Wnt-5a-derived hexapeptide, which inhibits breast cancer metastasis in vivo by targeting cell motility.

Technology Process of Foxy-5

There total 8 articles about Foxy-5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

For-Met-Asp(OtBu)-Gly-Cys(Trt)-Glu(OtBu)-Leu-OtBu → Foxy-5 (881188-51-8)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; diothiothreitol; at 15 - 30 ℃; Inert atmosphere;

Reference yield:

For-Met-Asp(OtBu)-Gly-Cys(Trt)-Glu(OtBu)-Leu-OH → Foxy-5 (881188-51-8)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; Cleland's reagent;

Reference yield:

Fmoc-Met-Asp(OtBu)-GIy-Cys(Trt)-GIu(OtBu)-Leu-OtBu → Foxy-5 (881188-51-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane

2: trifluoroacetic acid; chlorotriisopropylsilane; Cleland's reagent / 1.5 h

With chlorotriisopropylsilane; 1,8-diazabicyclo[5.4.0]undec-7-ene; trifluoroacetic acid; Cleland's reagent; In dichloromethane;

upstream raw materials:

N-formyl-L-methionine

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