Technology Process of 15-(acetyloxy)-3,8-dihydroxy-12,13-epoxytrichothec-9-en-4-yl 2-methylprop-2-enoate
There total 8 articles about 15-(acetyloxy)-3,8-dihydroxy-12,13-epoxytrichothec-9-en-4-yl 2-methylprop-2-enoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridinium p-toluenesulfonate;
In
ethanol;
at 50 ℃;
for 24h;
DOI:10.1021/jm00347a018
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 39 percent / SeO2 / dioxane; H2O / 24 h / Heating
2: 97 percent / pyridinium tosylate / CH2Cl2 / 24 h / Ambient temperature
3: 99 percent / 10percent aq. NaOH / methanol / 0.67 h / Ambient temperature
4: 98 percent / triethylamine / CH2Cl2 / 17 h / 0 °C
5: 88 percent / triethylamine / CH2Cl2 / 12 h / Ambient temperature
6: 54 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C
With
sodium hydroxide; selenium(IV) oxide; pyridinium p-toluenesulfonate; triethylamine;
In
1,4-dioxane; methanol; ethanol; dichloromethane; water;
DOI:10.1021/jm00347a018
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 98 percent / triethylamine / CH2Cl2 / 17 h / 0 °C
2: 88 percent / triethylamine / CH2Cl2 / 12 h / Ambient temperature
3: 54 percent / pyridinium tosylate / aq. ethanol / 24 h / 50 °C
With
pyridinium p-toluenesulfonate; triethylamine;
In
ethanol; dichloromethane;
DOI:10.1021/jm00347a018
