N-piperidin-4-yl-2-furamide

Base Information

• Chemical Name: N-piperidin-4-yl-2-furamide
• CAS No.: 836685-76-8
• Molecular Formula: C₁₀H₁₄N₂O₂
• Molecular Weight: 194.233
• Mol file: 836685-76-8.mol

Synonyms:

Chemical Property of N-piperidin-4-yl-2-furamide

Chemical Property:

Purity/Quality:

N-(PIPERIDIN-4-YL)FURAN-2-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-piperidin-4-yl-2-furamide

There total 4 articles about N-piperidin-4-yl-2-furamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ C10H14N2O2 (836685-76-8)

Guidance literature:

Reference yield:

C15H22N2O4 (1186299-33-1) → C10H14N2O2 (836685-76-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;

Reference yield:

2-furanoic acid (88-14-2) → C10H14N2O2 (836685-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; 1-hydroxy-7-aza-benzotriazole; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / dichloromethane / 12 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane;

upstream raw materials:

2-furanoic acid

1-(tert-butoxycarbonyl)-4-aminopiperidine

C₁₅H₂₂N₂O₄

Refernces

• 1、 -. "NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS". Page/Page column 35. . Retrieved 2009/09/08.