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2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride

Base Information Edit
  • Chemical Name:2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride
  • CAS No.:917497-70-2
  • Molecular Formula:C16H11FN6O*ClH
  • Molecular Weight:358.762
  • Hs Code.:
  • Mol file:917497-70-2.mol
2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride

Synonyms:

Suppliers and Price of 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • SC 144 hydrochloride
  • 10mg
  • $ 480.00
  • TRC
  • SC144 hydrochloride
  • 10mg
  • $ 205.00
  • Tocris
  • SC144 hydrochloride ≥98%(HPLC)
  • 10
  • $ 223.00
  • Tocris
  • SC144 hydrochloride ≥98%(HPLC)
  • 50
  • $ 934.00
  • Sigma-Aldrich
  • SC144 hydrochloride ≥98% (HPLC)
  • 25mg
  • $ 424.00
  • Sigma-Aldrich
  • SC144 hydrochloride ≥98% (HPLC)
  • 5mg
  • $ 100.00
  • Crysdot
  • SC144 hydrochloride 98+%
  • 10mg
  • $ 90.00
  • Crysdot
  • SC144 hydrochloride 98+%
  • 50mg
  • $ 402.00
  • Crysdot
  • SC144 hydrochloride 98+%
  • 100mg
  • $ 693.00
  • ChemScene
  • SC144 hydrochloride 99.04%
  • 100mg
  • $ 485.00
Total 9 raw suppliers
Chemical Property of 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride Edit
Chemical Property:
  • Melting Point:282 °C (decomp)(Solv: methanol (67-56-1)) 
  • Storage Temp.:?20°C 
  • Solubility.:DMSO: soluble5mg/mL, clear (warmed) 
Purity/Quality:

98%,99%, *data from raw suppliers

SC 144 hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36/39 
MSDS Files:
Useful:
  • Description SC144 is an orally bioavailable gp130 inhibitor. It inhibits phosphorylation of STAT1, STAT3, and Akt induced by leukemia inhibitory factor (LIF) and IL-6, but not IFN-γ, in OVCAR-8 ovarian cancer cells when used at a concentration of 20 μM. SC144 induces cell cycle arrest at the G0/G1 phase in MDA-MB-435 breast and HT-29 colorectal cancer cells and inhibits proliferation of 14 cancer cell lines, including prostate, ovarian, lung, breast, and colorectal cancer cells, with IC50 values ranging from 0.4 to 4 μM. It reduces tumor growth in OVCAR-8 and MDA-MB-435 mouse xenograft models.
  • Uses SC144 hydrochloride has been used: as a glycoprotein 130 (gp130) inhibitor to evaluate the effect of bazedoxifene on interleukin (IL-6) mediated cell viability in pancreatic cancer cellsas a gp130 inhibitor to study its effects on signal transducer and activator of transcription 3 (STAT3) activation in mesenchymal precursor?cells?(KMM)?cells as an interleukin 6 signal transducer (IL-6ST) inhibitor in media to test its ability to block serum-induced migration/invasion SC 144 Hydrochloride has been shown to have antitumor properties.
Technology Process of 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride

There total 1 articles about 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide-2-pyrazinecarboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
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