Technology Process of (2Z,5E)-octa-2,5-dien-1-ol
There total 3 articles about (2Z,5E)-octa-2,5-dien-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 2 steps
1.1: CH3MgCl / tetrahydrofuran / 1 h / 65 °C
1.2: 94 percent / CuCl / tetrahydrofuran; diethyl ether / 2 h / 65 °C
2.1: 88 percent / H2; quinoline / Lindlar catalyst / ethanol
With
quinoline; hydrogen; methylmagnesium chloride;
Lindlar's catalyst;
In
tetrahydrofuran; ethanol;
1.1: Metallation / 1.2: Alkylation / 2.1: Catalytic hydrogenation;
DOI:10.1016/S0009-3084(00)00137-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 84 percent / PBr3; pyridine / diethyl ether / 4 h / -10 °C
2.1: CH3MgCl / tetrahydrofuran / 1 h / 65 °C
2.2: 94 percent / CuCl / tetrahydrofuran; diethyl ether / 2 h / 65 °C
3.1: 88 percent / H2; quinoline / Lindlar catalyst / ethanol
With
pyridine; quinoline; hydrogen; methylmagnesium chloride; phosphorus tribromide;
Lindlar's catalyst;
In
tetrahydrofuran; diethyl ether; ethanol;
1.1: Bromination / 2.1: Metallation / 2.2: Alkylation / 3.1: Catalytic hydrogenation;
DOI:10.1016/S0009-3084(00)00137-7