3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Base Information

Chemical Name:3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid
CAS No.:777857-51-9
Molecular Formula:C₂₂H₁₇FO₅
Molecular Weight:380.372
Hs Code.:
DSSTox Substance ID:DTXSID801130872
Mol file:777857-51-9.mol

Synonyms:3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid;777857-51-9;3-[3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl]propanoic acid;DTXSID801130872;BBL030051;MFCD03660177;STL372145;AKOS001892312;3-[3-(4-fluorophenyl)-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl]propanoic acid;VS-09583;CS-0317183;3-(4-Fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-6-propanoic acid

Suppliers and Price of 3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:380.10600180
Heavy Atom Count:28
Complexity:666

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=O)OC2=C(C3=C(C=C12)C(=CO3)C4=CC=C(C=C4)F)C)CCC(=O)O

Technology Process of 3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

There total 4 articles about 3-(3-(4-fluorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 670241-98-2
ethyl 3-{7'-[2''-(4'''-fluorophenyl)-2''-oxoethoxy]-4',8'-dimethyl-2'-oxochromen-3'-yl}propanoate

: 777857-51-9
3-{3'-(4''-fluorophenyl)-5',9'-dimethyl-7'-oxofuro[3,2-g]chromen-6'-yl}propanoic acid

Guidance literature:: With sodium hydroxide; Heating;
DOI:10.1023/B:RUBI.0000030137.88504.10

Reference yield:

: 1501-06-0
diethyl 2-acetylglutarate

: 777857-51-9
3-{3'-(4''-fluorophenyl)-5',9'-dimethyl-7'-oxofuro[3,2-g]chromen-6'-yl}propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / HCl / ethanol / 20 °C

2: 86 percent / Na₂CO₃ / acetone / 50 - 56 °C

3: 92 percent / NaOH / Heating

With hydrogenchloride; sodium hydroxide; sodium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/B:RUBI.0000030137.88504.10

Reference yield:

: 608-25-3
2-methylbenzene-1,3-diol

: 777857-51-9
3-{3'-(4''-fluorophenyl)-5',9'-dimethyl-7'-oxofuro[3,2-g]chromen-6'-yl}propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / HCl / ethanol / 20 °C

2: 86 percent / Na₂CO₃ / acetone / 50 - 56 °C

3: 92 percent / NaOH / Heating

With hydrogenchloride; sodium hydroxide; sodium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/B:RUBI.0000030137.88504.10