Technology Process of bis(6-chloropyridin-3-yl)iodonium chloride
There total 1 articles about bis(6-chloropyridin-3-yl)iodonium chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium; 1-chloro-2-(dichloro-λ3-iodanyl)-ethene;
In
diethyl ether; hexane;
at -78 - 20 ℃;
for 4h;
DOI:10.1002/anie.200501745
- Guidance literature:
-
Multi-step reaction with 5 steps
1: (R,R)-bis(α-methylbenzyl)amine hydrochloride; BuLi / tetrahydrofuran; dimethylformamide; hexane / 4 h / -45 °C
2: 83 percent / NaBH4 / methanol / 2.5 h / -98 - -60 °C
3: Et3N / CH2Cl2 / 4 h / 20 °C
4: TFA / CH2Cl2 / 15 h / 20 °C
5: 26.5 mg / CHCl3 / 60 h / Heating
With
sodium tetrahydroborate; n-butyllithium; (R,R)-(+)-bis[alpha-methylbenzyl]amine hydrochloride; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; hexane; dichloromethane; chloroform; N,N-dimethyl-formamide;
DOI:10.1002/anie.200501745
