Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate

Base Information

• Chemical Name: Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate
• CAS No.: 886361-77-9
• Molecular Formula: C₁₃H₁₁NO₄S
• Molecular Weight: 277.301
• DSSTox Substance ID: DTXSID101249961
• Mol file: 886361-77-9.mol

Synonyms:ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate;ethyl 5-(3-nitrophenyl)thiophene-2-carboxylate;886361-77-9;DTXSID101249961;MFCD08056631;AKOS005070643;ethyl5-(3-nitrophenyl)thiophene-2-carboxylate;4Z-0716

Chemical Property of Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate

Chemical Property:

• Melting Point: 88-91°
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 277.04087901
• Heavy Atom Count: 19
• Complexity: 344

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)C1=CC=C(S1)C2=CC(=CC=C2)[N+](=O)[O-]

Technology Process of Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate

There total 1 articles about Ethyl 5-(3-nitrophenyl)-2-thiophenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C10H9NO3S + potassium ethyl thioglycolate → ethyl 5-(4-nitrophenyl)thiophene-2-carboxylate (886361-77-9)

Guidance literature:

With potassium carbonate; In ethanol; at 80 ℃; for 1h; Reflux;

DOI:10.1016/j.tetlet.2016.01.055