Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester

Base Information

• Chemical Name: Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester
• CAS No.: 113866-70-9
• Molecular Formula: C₂₄H₃₅BrO₆
• Molecular Weight: 499.442
• Mol file: 113866-70-9.mol

Synonyms:

Chemical Property of Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester

There total 2 articles about Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

paraguerol 7,16,19-triacetate (83115-37-1) → Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-3-hydroxy-1a-hydroxymethyl-5,7b-dimethyl-5-(S)-oxiranyl-1a,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-1H-cyclopropa[a]phenanthren-9-yl ester (132342-74-6) + parguerol (83115-36-0) + Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-3-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-1a-hydroxymethyl-5,7b-dimethyl-1a,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-1H-cyclopropa[a]phenanthren-9-yl ester (113866-69-6) + Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester (113866-70-9)

Guidance literature:

With sodium carbonate; In methanol; for 4h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature;

DOI:10.1246/bcsj.63.3066

Reference yield:

paraguerol 7,16,19-triacetate (83115-37-1) → parguerol (83115-36-0) + Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-3-acetoxy-1a-hydroxymethyl-5,7b-dimethyl-5-(S)-oxiranyl-1a,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-1H-cyclopropa[a]phenanthren-9-yl ester (113866-73-2) + Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-3-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-1a-hydroxymethyl-5,7b-dimethyl-1a,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-1H-cyclopropa[a]phenanthren-9-yl ester (113866-69-6) + Acetic acid (1aS,1bS,3R,3aR,5S,7bR,9R,9aR)-9-acetoxy-5-((R)-1-bromo-2-hydroxy-ethyl)-3-hydroxy-5,7b-dimethyl-1,1b,2,3,3a,4,5,6,7b,8,9,9a-dodecahydro-cyclopropa[a]phenanthren-1a-ylmethyl ester (113866-70-9)

Guidance literature:

With sodium carbonate; In methanol; for 4h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature;

DOI:10.1246/bcsj.63.3066

upstream raw materials:

paraguerol 7,16,19-triacetate