4-Dimethylamino-3'-trifluoromethylbiphenyl

Base Information

Chemical Name:4-Dimethylamino-3'-trifluoromethylbiphenyl
CAS No.:844856-48-0
Molecular Formula:C₁₅H₁₄F₃N
Molecular Weight:265.278
Hs Code.:
DSSTox Substance ID:DTXSID301202581
Mol file:844856-48-0.mol

Synonyms:4-Dimethylamino-3'-trifluoromethylbiphenyl;844856-48-0;N,N-Dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine;SOQSNCQDKHZSFE-UHFFFAOYSA-N;DTXSID301202581;SB81840;Dimethyl-(3'-(trifluoromethyl)biphenyl-4-yl)-amine;N,N-dimethyl-3'-(trifluoromethyl)biphenyl-4-amine;N,N-Dimethyl-3'-(trifluoromethyl)[1,1'-biphenyl]-4-amine

Suppliers and Price of 4-Dimethylamino-3'-trifluoromethylbiphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-DIMETHYLAMINO-3'-TRIFLUOROMETHYLBIPHENYL
5g
$ 1943.00

Rieke Metals
4-DIMETHYLAMINO-3'-TRIFLUOROMETHYLBIPHENYL
1g
$ 809.00

Crysdot
N,N-Dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine 97%
1g
$ 437.00

Crysdot
N,N-Dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine 97%
5g
$ 1177.00

Alichem
Dimethyl-(3'-(trifluoromethyl)biphenyl-4-yl)-amine
1g
$ 1445.30

Alichem
Dimethyl-(3'-(trifluoromethyl)biphenyl-4-yl)-amine
500mg
$ 863.90

Total 2 raw suppliers

Chemical Property of 4-Dimethylamino-3'-trifluoromethylbiphenyl

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:265.10783394
Heavy Atom Count:19
Complexity:280

Purity/Quality:

99% ^*data from raw suppliers

4-DIMETHYLAMINO-3'-TRIFLUOROMETHYLBIPHENYL ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)C(F)(F)F

Technology Process of 4-Dimethylamino-3'-trifluoromethylbiphenyl

There total 5 articles about 4-Dimethylamino-3'-trifluoromethylbiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 937-00-8
3-trifluoromethyl-thiophenol

: 93296-10-7
(4-(dimethylamino)phenyl)zinc(II) chloride

: 844856-48-0
N,N-dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine

Guidance literature:: 3-trifluoromethyl-thiophenol; With methylzinc chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

(4-(dimethylamino)phenyl)zinc(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

In toluene; at 120 ℃; for 24h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.7b03145

Reference yield: 83.0%

: 20738-59-4
4-(dimethylamino)phenyl 4-methylbenzenesulfonate

: C₁₄H₈F₆Zn*MgBr*2LiCl

: 844856-48-0
N,N-dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine

Guidance literature:: In 2-methyltetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 80 ℃; for 0.5h; Glovebox; Microwave irradiation; Inert atmosphere;
DOI:10.1177/17475198211026479

Reference yield: 81.0%

: C₁₃H₁₉NO₂

: C₁₄H₈F₆Zn*MgBr*2LiCl

: 844856-48-0
N,N-dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine

Guidance literature:: In 2-methyltetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 80 ℃; for 0.5h; Glovebox; Microwave irradiation; Inert atmosphere;
DOI:10.1177/17475198211026479