Vonoprazan Impurity 2

Base Information

• Chemical Name: Vonoprazan Impurity 2
• CAS No.: 881733-36-4
• Molecular Formula: C₁₇H₁₆FN₃O₂S
• Molecular Weight: 345.397
• Mol file: 881733-36-4.mol

Synonyms:

Chemical Property of Vonoprazan Impurity 2

Chemical Property:

• Boiling Point: 534.7±60.0 °C(Predicted)
• PKA: 9.11±0.10(Predicted)
• Density: 1.31±0.1 g/cm3(Predicted)

Purity/Quality:

NLT 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Vonoprazan Impurity 2

There total 1 articles about Vonoprazan Impurity 2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl {[5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate (881678-31-5) → 1-[5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine (881733-36-4)

Guidance literature:

tert-butyl {[5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 3h;

With water; sodium hydrogencarbonate; In dichloromethane;

upstream raw materials:

tert-butyl {[5-(4-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamate

Refernces

• 1、 -. "Acid secretion inhibitor". Page/Page column 58-59. . Retrieved 2008/06/13.