9H-PURINE-6-ETHANAMINE

Base Information

• Chemical Name: 9H-PURINE-6-ETHANAMINE
• CAS No.: 89854-22-8
• Molecular Formula: C₇H₉N₅
• Molecular Weight: 163.182
• Mol file: 89854-22-8.mol

Synonyms:

Chemical Property of 9H-PURINE-6-ETHANAMINE

Chemical Property:

Purity/Quality:

9H-Purine-6-ethanamine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9H-PURINE-6-ETHANAMINE

There total 3 articles about 9H-PURINE-6-ETHANAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

6-(2-aminoethyl)-9-(tetrahydropyran-2-yl)purine → 6-(2'-aminoethyl)-9H-purine (89854-22-8)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 6h;

DOI:10.1002/ejoc.200600545

Reference yield:

6-ethenyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (220525-84-8) → 6-(2'-aminoethyl)-9H-purine (89854-22-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / NH₃ / ethanol / 2 h / 20 °C

2: 61 percent / HCl / methanol / 6 h / 20 °C

With hydrogenchloride; ammonia; In methanol; ethanol;

DOI:10.1002/ejoc.200600545

Reference yield:

→ 6-(2'-aminoethyl)-9H-purine (89854-22-8)

Guidance literature:

3-Puryl-(6)-propionsaeureamid , wss. NaOBr-Lsg. (Loesen bei Raumtemp., dann 1 h bei 60-70gradC ) ; Ausb. 30 percent;

upstream raw materials:

6-ethenyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

Refernces

• 1、 Kuchar, Martin,Pohl, Radek,Votruba, Ivan,Hocek, Michal. "Synthesis of purines bearing functionalized C-substituents by the conjugate addition of nucleophiles to 6-vinylpurines and 6-ethynylpurines". . p. 5083 - 5098. Retrieved 2007/10/03.