tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate

Base Information

Chemical Name:tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate
CAS No.:161805-78-3
Molecular Formula:C₁₂H₂₂ClNO₃
Molecular Weight:263.765
Hs Code.:
DSSTox Substance ID:DTXSID401125255

Synonyms:tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate;161805-78-3;Tert-butyl N-[(3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl]carbamate;DTXSID401125255;MFCD32644590;AKOS037648863;BS-15872;CS-0162407;D81412;Carbamic acid, [1-(chloroacetyl)-2-methylbutyl]-, 1,1-dimethylethyl ester, [S-(R*,R*)]-

Suppliers and Price of tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:263.1288213
Heavy Atom Count:17
Complexity:273

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(C)C(C(=O)CCl)NC(=O)OC(C)(C)C
Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)CCl)NC(=O)OC(C)(C)C

Technology Process of tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate

There total 4 articles about tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 497106-85-1
[(1S,2R)-1-(2-Diazo-acetyl)-2-methyl-butyl]-carbamic acid tert-butyl ester

: 161805-78-3
[(1S,2R)-1-(2-Chloro-acetyl)-2-methyl-butyl]-carbamic acid tert-butyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 0 ℃; for 1h;
DOI:10.1021/jm00038a005

Reference yield:

: 13139-16-7,35264-07-4,55721-65-8,55780-90-0,116194-21-9
Boc-L-aIle-OH

: 161805-78-3
[(1S,2R)-1-(2-Chloro-acetyl)-2-methyl-butyl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methylmorpholine / tetrahydrofuran / 0.33 h / -25 - -20 °C

2: diethyl ether / a) 0 deg C, 2 h, b) RT, overnight

3: HCl / dioxane / 1 h / 0 °C

With 4-methyl-morpholine; hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; diethyl ether;
DOI:10.1021/jm00038a005

Reference yield:

: C₁₆H₂₉NO₆

: 161805-78-3
[(1S,2R)-1-(2-Chloro-acetyl)-2-methyl-butyl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / a) 0 deg C, 2 h, b) RT, overnight

2: HCl / dioxane / 1 h / 0 °C

With hydrogenchloride; In 1,4-dioxane; diethyl ether;
DOI:10.1021/jm00038a005