3-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-PHENYLAMINE

Base Information

• Chemical Name: 3-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-PHENYLAMINE
• CAS No.: 956441-27-3
• Molecular Formula: C₁₂H₁₅N₃
• Molecular Weight: 201.271
• Mol file: 956441-27-3.mol

Synonyms:

Chemical Property of 3-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-PHENYLAMINE

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-PHENYLAMINE

There total 3 articles about 3-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-PHENYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3,5-dimethyl-1-[(m-nitrophenyl)methyl]-1H-pyrazole → m-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]aniline (956441-27-3)

Guidance literature:

3,5-dimethyl-1-[(m-nitrophenyl)methyl]-1H-pyrazole; With iron; acetic acid; In ethanol; for 18h; Inert atmosphere; Reflux;

With sodium hydroxide; In ethanol; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.poly.2014.11.004

Reference yield:

1-bromomethyl-3-nitrobenzene (3958-57-4) → m-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]aniline (956441-27-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene / 18 h / Reflux; Inert atmosphere

2.1: iron; acetic acid / ethanol / 18 h / Inert atmosphere; Reflux

2.2: 20 °C / Inert atmosphere

With iron; acetic acid; In ethanol; toluene;

DOI:10.1016/j.poly.2014.11.004

Reference yield:

3,5-dimethyl-1H-pyrazole (67-51-6) → m-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]aniline (956441-27-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene / 18 h / Reflux; Inert atmosphere

2.1: iron; acetic acid / ethanol / 18 h / Inert atmosphere; Reflux

2.2: 20 °C / Inert atmosphere

With iron; acetic acid; In ethanol; toluene;

DOI:10.1016/j.poly.2014.11.004

upstream raw materials:

1-bromomethyl-3-nitrobenzene

3,5-dimethyl-1H-pyrazole

Refernces