5-Chlorohex-5-enenitrile

Base Information

• Chemical Name: 5-Chlorohex-5-enenitrile
• CAS No.: 951887-60-8
• Molecular Formula: C₆H₈ClN
• Molecular Weight: 129.589
• Mol file: 951887-60-8.mol

Synonyms:

Chemical Property of 5-Chlorohex-5-enenitrile

Chemical Property:

Purity/Quality:

5-chloro-5-hexenenitrile 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Chlorohex-5-enenitrile

There total 1 articles about 5-Chlorohex-5-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5-hexynonitrile (14918-21-9) → 5-chloro-5-hexenenitrile (951887-60-8)

Guidance literature:

With hydrogenchloride; chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II); triphenylphosphine; In diethyl ether; 1,2-dichloro-ethane; at 20 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201505144

upstream raw materials:

5-hexynonitrile

Refernces

• 1、 Ebule, Rene,Liang, Shengzong,Hammond, Gerald B.,Xu, Bo. "Chloride-tolerant gold(I)-catalyzed regioselective hydrochlorination of alkynes". . p. 6798 - 6801. Retrieved 2017/11/09.
• 2、 Dérien, Sylvie,Klein, Hubert,Bruneau, Christian. "Selective Ruthenium-Catalyzed Hydrochlorination of Alkynes: One-Step Synthesis of Vinylchlorides". supporting information. p. 12112 - 12115. Retrieved 2015/10/12.