1-(methylthio)-2-aminofluorene

Base Information

• Chemical Name: 1-(methylthio)-2-aminofluorene
• CAS No.: 21921-55-1
• Molecular Formula: C₁₄H₁₃NS
• Molecular Weight: 227.33
• Mol file: 21921-55-1.mol

Synonyms:

Chemical Property of 1-(methylthio)-2-aminofluorene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(methylthio)-2-aminofluorene

There total 2 articles about 1-(methylthio)-2-aminofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Hydroxy-2-acetylaminofluoren (53-95-2) → 2-Amino-3-methylmercapto-fluoren (13111-11-0) + 1-(methylthio)-2-aminofluorene (21921-55-1)

Guidance literature:

With buffer pH=6.8; partially purified hamster hepatic AHAT; In ethanol; at 37 ℃; rate of methylthio adduct formation, other 7-substituted 2-(N-hydroxyacetamido)fluorenes;

DOI:10.1021/jm00148a014

Reference yield:

N-acetyl-DL-methionine (1115-47-5) + NA-AAF (6098-44-8) → 2-Amino-3-methylmercapto-fluoren (13111-11-0) + 1-(methylthio)-2-aminofluorene (21921-55-1)

Guidance literature:

With hydrogenchloride; phosphate buffer; Multistep reaction. Title compound not separated from byproducts; 1.) 95percent aq. ethanol, 48 deg C, 2.5 h, 2.) reflux, 8 h;

DOI:10.1021/jm00148a014

upstream raw materials:

N-acetyl-DL-methionine

NA-AAF

N-Hydroxy-2-acetylaminofluoren

Refernces