Technology Process of 1-CYCLOHEXENECARBONYL CHLORIDE
There total 8 articles about 1-CYCLOHEXENECARBONYL CHLORIDE which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
oxalyl dichloride;
N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride; ethanol; oxalic acid diethyl ester / 5,5-dimethyl-1,3-cyclohexadiene; mineral oil / 14 h / 20 °C
1.2: 1 h
1.3: 14 h
2.1: sodium hydroxide / water / 1 h / Reflux
2.2: pH 2
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 17 h / 0 - 20 °C
With
oxalyl dichloride; ethanol; sodium hydride; N,N-dimethyl-formamide; oxalic acid diethyl ester; sodium hydroxide;
In
5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; water; mineral oil;
DOI:10.1021/acs.orglett.5b00337
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 1 h / Reflux
1.2: pH 2
2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 17 h / 0 - 20 °C
With
oxalyl dichloride; N,N-dimethyl-formamide; sodium hydroxide;
In
dichloromethane; water;
DOI:10.1021/acs.orglett.5b00337
