(S)-(-)-HigenaMine HydrobroMide

Base Information

• Chemical Name: (S)-(-)-HigenaMine HydrobroMide
• CAS No.: 105990-27-0
• Molecular Formula: BrH*C₁₆H₁₇NO₃
• Molecular Weight: 352.228
• Mol file: 105990-27-0.mol

Synonyms:

Chemical Property of (S)-(-)-HigenaMine HydrobroMide

Chemical Property:

• Melting Point: >250°C (dec.)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(S)-(-)-HigenamineHydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (S)-(-)-HigenaMine HydrobroMide has been used in the preparation of (-)-Higenamine (H325800) 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-hydrobromide-(1S)-6,7-isoquinolinediol has been used in the preparation of (-)-Higenamine (H325800)

Technology Process of (S)-(-)-HigenaMine HydrobroMide

There total 2 articles about (S)-(-)-HigenaMine HydrobroMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(R)-6,7-dimethoxy-l-(p-methoxyphenylmethyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide → (R)-(+)-higenamine hydrobromide (105990-27-0)

Guidance literature:

(R)-6,7-dimethoxy-l-(p-methoxyphenylmethyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide; With boron tribromide; In dichloromethane; at -78 - 0 ℃; for 3h;

With ethanol; water; In dichloromethane; for 1h;

Reference yield: 76.0%

(S)-6,7-dimethoxy-1-(p-methoxyphenylmethyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide → 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide (105990-27-0)

Guidance literature:

(S)-6,7-dimethoxy-1-(p-methoxyphenylmethyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide; With boron tribromide; In dichloromethane; at -78 - 0 ℃; for 3h;

With ethanol; water; In dichloromethane;