Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one

Base Information

Chemical Name:Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one
CAS No.:133886-44-9
Molecular Formula:C₁₄H₁₇NO₃S
Molecular Weight:279.36
Hs Code.:
DSSTox Substance ID:DTXSID001161700

Synonyms:133886-44-9;DTXSID001161700;Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one

Suppliers and Price of Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:279.09291458
Heavy Atom Count:19
Complexity:444

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC3CC(=O)CC3C2

Technology Process of Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one

There total 4 articles about Hexahydro-2-[(4-methylphenyl)sulfonyl]cyclopenta[c]pyrrol-5(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133886-40-5
N-tosyl-N-allylpropargylamine

: 133886-44-9
2-(Toluene-4-sulfonyl)-hexahydro-cyclopenta[c]pyrrol-5-one

: 133886-43-8
2,3,3a,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-cyclopenta[c]pyrrol-5(1H)-one

Guidance literature:: With silica gel; Yield given. Multistep reaction. Yields of byproduct given; 1.) Et₂O, r.t., 14-18 h, 2.) 70 deg C, 2.5 h;
DOI:10.1016/S0040-4039(00)60352-0

Reference yield:

: 50487-71-3
4-methyl-N-(2-propenyl)benzenesulfonamide

: dicobalthexacarbonyl propargyl alcohol complex

: 133886-44-9
2-(Toluene-4-sulfonyl)-hexahydro-cyclopenta[c]pyrrol-5-one

: 133886-43-8
2,3,3a,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-cyclopenta[c]pyrrol-5(1H)-one

Guidance literature:: With trimethylamine-N-oxide; boron trifluoride diethyl etherate; Yield given. Multistep reaction. Yields of byproduct given; 1) CH₂Cl₂, 10 min at -78 deg C; 2) CH₂Cl₂, -78 deg C, 30 min at room temp.; 3) CH₂Cl₂, 1 h at room temp.;
DOI:10.1016/S0040-4039(00)71257-3

Reference yield:

: 42268-68-8
allylpropargylamine

: 133886-44-9
2-(Toluene-4-sulfonyl)-hexahydro-cyclopenta[c]pyrrol-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / pyridine

2: 2.) silica gel, O₂ / 1.) Et₂O, r.t., 14-18 h, 2.) 70 deg C, 2.5 h

With pyridine; oxygen; silica gel;
DOI:10.1016/S0040-4039(00)60352-0