sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Base Information

Chemical Name:sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate
CAS No.:1375799-59-9
Molecular Formula:C₁₃H₁₃N₈O₂*Na
Molecular Weight:336.288
Hs Code.:

Synonyms:

Suppliers and Price of sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
MolidustatSodiumSalt
25mg
$ 305.00

TRC
MolidustatSodiumSalt
1mg
$ 50.00

Total 1 raw suppliers

Chemical Property of sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Chemical Property:

Density:1.558 at 20℃

Purity/Quality:

≥98% ^*data from raw suppliers

MolidustatSodiumSalt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Molidustat Sodium Salt is a salt form of Molidustat (CAS 1154028-82-6) which is used in the synthesis and characterization of new polydentate tetrazole as multiple screening compounds. Investigational therapies for renal disease-induced anemia.

Technology Process of sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

There total 5 articles about sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

: 1375799-61-3
1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-ol

: 1375799-59-9
sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Guidance literature:: With triethylamine; sodium hydroxide; In methanol; water; at 50 - 60 ℃; for 1h; Reagent/catalyst;

Reference yield:

: 1375799-60-2
methyl 2-(1H-1,2,3-triazol-1-yl)acrylate

: 1375799-59-9
sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4 h / Heating

2.1: trifluoroacetic acid / ethyl acetate / 24 h / Reflux

2.2: 0.25 h / pH 5

3.1: sodium hydroxide / water; methanol / 3 h / 0 - 50 °C

With trifluoroacetic acid; sodium hydroxide; In methanol; water; ethyl acetate;

Reference yield:

: 5767-36-2
4-(6-hydrazinopyrimidin-4-yl)morpholine

: 1375799-59-9
sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / ethyl acetate / 18 h / Reflux; Large scale

2.1: triethylamine / water; methanol / 1 h / 60 °C / Large scale

2.2: 1 h / 60 °C / Large scale

With triethylamine; trifluoroacetic acid; In methanol; water; ethyl acetate;
DOI:10.1002/cmdc.201700783