3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Base Information

Chemical Name:3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid
CAS No.:1260385-82-7
Molecular Formula:C₆H₄N₄O₂
Molecular Weight:164.123
Hs Code.:
European Community (EC) Number:822-216-1

Synonyms:3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid;1260385-82-7;2H-triazolo[4,5-b]pyridine-6-carboxylic acid;SCHEMBL14121253;SCHEMBL18528868;1H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE-6-CARBOXYLIC ACID;AKOS024015655;CS-0225652;EN300-124555;Z1255386462

Suppliers and Price of 3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
3H-[1,2,3]Triazolo[4,5-b]pyridine-6-carboxylicacid
10g
$ 3661.00

AK Scientific
3H-[1,2,3]Triazolo[4,5-b]pyridine-6-carboxylicacid
5g
$ 2501.00

Total 2 raw suppliers

Chemical Property of 3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Chemical Property:

XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:164.03342538
Heavy Atom Count:12
Complexity:198

Purity/Quality:

97% ^*data from raw suppliers

3H-[1,2,3]Triazolo[4,5-b]pyridine-6-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=NC2=NNN=C21)C(=O)O

Technology Process of 3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

There total 5 articles about 3H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1216004-74-8
1H-[1,2,3]-triazolo[4,5-b]pyridine-6-carboxylic acid methyl ester

: 1260385-82-7
1H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Guidance literature:: 1H-[1,2,3]-triazolo[4,5-b]pyridine-6-carboxylic acid methyl ester; With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

With hydrogenchloride; In water; pH=3;

Reference yield:

: 104685-75-8
methyl 2-amino-3-nitropyridine-5-carboxylate

: 1260385-82-7
1H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / 2 h / 20 °C / Inert atmosphere

2.1: hydrogen / palladium on activated charcoal / methanol / 20 °C

3.1: sodium nitrite; sulfuric acid / water / 1.08 h / -5 - 0 °C / Inert atmosphere

4.1: sodium hydroxide; water / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

4.2: pH 3

With sulfuric acid; water; hydrogen; sodium hydroxide; sodium nitrite; palladium on activated charcoal; In tetrahydrofuran; methanol; water;

Reference yield:

: 1415312-40-1
C₉H₉N₃O₅

: 1260385-82-7
1H-[1,2,3]triazolo[4,5-b]pyridine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium on activated charcoal / methanol / 20 °C

2.1: sodium nitrite; sulfuric acid / water / 1.08 h / -5 - 0 °C / Inert atmosphere

3.1: sodium hydroxide; water / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

3.2: pH 3

With sulfuric acid; water; hydrogen; sodium hydroxide; sodium nitrite; palladium on activated charcoal; In tetrahydrofuran; methanol; water;