3,21-dihydroxypregnenane

Base Information

• Chemical Name: 3,21-dihydroxypregnenane
• CAS No.: 16109-79-8
• Molecular Formula: C₂₁H₃₆O₂
• Molecular Weight: 320.516
• Mol file: 16109-79-8.mol

Synonyms:

Chemical Property of 3,21-dihydroxypregnenane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,21-dihydroxypregnenane

There total 22 articles about 3,21-dihydroxypregnenane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β-hydroxy-5β-pregnene-(17(20)seqtrans)-oic acid-(21) (30040-43-8,59648-69-0) → 3α,21-dihydroxy-5β-pregnane (16109-79-8,1227043-63-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium; amyl alcohol

2: diethyl ether

3: ethanol; sodium

With diethyl ether; ethanol; pentan-1-ol; sodium;

DOI:10.1080/03014223.2000.9518225

Reference yield:

16β.17-dibromo-3β-acetoxy-5β-pregnanone-(20) (2066-34-4) → 3α,21-dihydroxy-5β-pregnane (16109-79-8,1227043-63-1)

Guidance literature:

Multi-step reaction with 4 steps

1: methanol. KOH-solution

2: sodium; amyl alcohol

3: diethyl ether

4: ethanol; sodium

With potassium hydroxide; diethyl ether; ethanol; pentan-1-ol; sodium;

DOI:10.1080/03014223.2000.9518225

Reference yield:

3β-hydroxy-5β-pregnanoic acid-(21) (104538-76-3) → 3α,21-dihydroxy-5β-pregnane (16109-79-8,1227043-63-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium; amyl alcohol

2: diethyl ether

3: ethanol; sodium

With diethyl ether; ethanol; pentan-1-ol; sodium;

DOI:10.1080/03014223.2000.9518225

upstream raw materials:

3α-hydroxy-5β-pregnanoic acid-(21)-methyl ester

3α-hydroxy-5β-pregnanoic acid-(21)

3β-hydroxy-5β-pregnanoic acid-(21)

3β-hydroxy-5β-pregnene-(17(20)seqtrans)-oic acid-(21)

Refernces