1,2-⁽¹³⁾C₂-α-ketoglutaric acid

Base Information

• Chemical Name: 1,2-⁽¹³⁾C₂-α-ketoglutaric acid
• CAS No.: 123953-28-6
• Molecular Formula: C₅H₆O₅
• Molecular Weight: 148.078
• Mol file: 123953-28-6.mol

Synonyms:

Chemical Property of 1,2-⁽¹³⁾C₂-α-ketoglutaric acid

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-⁽¹³⁾C₂-α-ketoglutaric acid

There total 3 articles about 1,2-⁽¹³⁾C₂-α-ketoglutaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-[1,2-13C]-glutamic acid (115473-56-8,108395-12-6) → 1,2-(13)C2-α-ketoglutaric acid (123953-28-6,108395-15-9) + succinic semialdehyde

Guidance literature:

With Clostridium sp. L-glutamate dehydrogenase; NADH; diothiothreitol; In aq. phosphate buffer; at 30 ℃; pH=8; Enzymatic reaction;

DOI:10.1021/ol3031186

Reference yield:

L-[1,2-13C]-glutamic acid (115473-56-8,108395-12-6) → 1,2-(13)C2-α-ketoglutaric acid (123953-28-6,108395-15-9)

Guidance literature:

With NADH oxidase; L-glutamate dehydrogenase; Enzymatic reaction;

DOI:10.1039/c2ob26981c

Reference yield:

→ 1,2-(13)C2-α-ketoglutaric acid (123953-28-6,108395-15-9)

Guidance literature:

With hydrogenchloride; water; at 20 ℃; Reflux;

upstream raw materials:

L-[1,2-¹³C]-glutamic acid