2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride

Base Information

Chemical Name:2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride
CAS No.:334477-59-7
Molecular Formula:C₁₁H₁₅FN₂*2ClH
Molecular Weight:267.174
Hs Code.:

Synonyms:

Suppliers and Price of 2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(S)-2-(4-Fluoro-2-methylphenyl)-piperazinedihydrochloride 95+%
1g
$ 2492.00

Crysdot
(S)-2-(4-Fluoro-2-methylphenyl)piperazinedihydrochloride 95+%
1g
$ 1477.00

Chemenu
(S)-2-(4-Fluoro-2-methylphenyl)piperazinedihydrochloride 95%
1g
$ 1391.00

Total 6 raw suppliers

Chemical Property of 2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride

Chemical Property:

Vapor Pressure:6.96E-06mmHg at 25°C

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-(4-Fluoro-2-methylphenyl)-piperazinedihydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride

There total 1 articles about 2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.5%

: 334477-72-4
(3S)-3-(4-fluoro-2-methylphenyl)-2-piperazinone (S)-mandelate

: 334477-59-7,1434126-86-9
(2S)-2-(4-fluoro-2-methylphenyl)piperazine dihydrochloride

Guidance literature:: (3S)-3-(4-fluoro-2-methylphenyl)-2-piperazinone (S)-mandelate; With tetrabutylammomium bromide; In tetrahydrofuran; at 25 - 40 ℃; under 760.051 Torr; Inert atmosphere; Large scale reaction;

With sodium tetrahydroborate; In tetrahydrofuran; at 25 ℃; for 2h; under 760.051 Torr; Reagent/catalyst; Concentration; Temperature; Solvent; optical yield given as %ee; Further stages; Reactivity; Inert atmosphere; Large scale reaction;
DOI:10.1021/op8002823