(3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one

Base Information

Chemical Name:(3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one
CAS No.:1312077-05-6
Molecular Formula:C₁₂H₁₁NO
Molecular Weight:185.225
Hs Code.:
UNII:AWC4KM8D9M
Mol file:1312077-05-6.mol

Synonyms:1312077-05-6;3-Keto-pai;AWC4KM8D9M;(3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one;(3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one;Rasagiline metabolite, 3-keto-pai;(R)-3-(Prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 2,3-dihydro-3-(2-propyn-1-ylamino)-, (3R)-;starbld0027967;UNII-AWC4KM8D9M;SCHEMBL1986900;(3R)-3-(Prop-2-yn-1-ylamino)indan-1-one (3-Ketorasagiline);2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one, (3R)-;(3R)-3-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-inden-1-one;(3R)-3-(Prop-2-yn-1-ylamino)indan-1-one;(3R)-3-(Prop-2-ynylamino)-2,3-dihydroinden-1-one;(3R)-3-[(Prop-2-yn-1-yl)amino]-2,3-dihydro-1H-inden-1-one

Suppliers and Price of (3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one
50mg
$ 1190.00

Total 6 raw suppliers

Chemical Property of (3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one

Chemical Property:

Melting Point:51-54°C
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly, He
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:185.084063974
Heavy Atom Count:14
Complexity:275

Purity/Quality:

98% ^*data from raw suppliers

(3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CCNC1CC(=O)C2=CC=CC=C12
Isomeric SMILES:C#CCN[C@@H]1CC(=O)C2=CC=CC=C12
Uses (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one, is a building block in the preparation of Rasagiline (R126000), which is a selective irreversible MAO-B inhibitor. Rasagiline is also an Antiparkinsonian agent.

Technology Process of (3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one

There total 1 articles about (3R)-3-(prop-2-ynylamino)-2,3-dihydroinden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: