Technology Process of C15H17FN2O3
There total 5 articles about C15H17FN2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
8-Acetylamino-6-fluoro-5-methyl-1-tetralone;
With
potassium tert-butylate;
In
tetrahydrofuran; tert-butyl alcohol;
at 5 ℃;
for 0.166667h;
With
butyl nitrate;
In
tetrahydrofuran; tert-butyl alcohol;
for 1h;
acetic anhydride;
Further stages;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dipotassium peroxodisulfate / acetonitrile; water / 8 h / 30 °C
2.1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 0.17 h / 5 °C
2.2: 1 h
With
dipotassium peroxodisulfate; potassium tert-butylate;
In
tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid / 0.5 h / 10 °C
2.1: bromine; acetic acid; sodium acetate / 2 h / 60 - 80 °C
3.1: n-butyllithium / tetrahydrofuran / 1.5 h / -78 °C
3.2: 1 h / -78 - 20 °C
4.1: dipotassium peroxodisulfate / acetonitrile; water / 8 h / 30 °C
5.1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 0.17 h / 5 °C
5.2: 1 h
With
dipotassium peroxodisulfate; n-butyllithium; sulfuric acid; potassium tert-butylate; bromine; sodium acetate; acetic acid;
In
tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;