4-(4-Bromobenzyloxy)benzaldehyde

Base Information

• Chemical Name: 4-(4-Bromobenzyloxy)benzaldehyde
• CAS No.: 149833-95-4
• Molecular Formula: C14H11 Br O2
• Molecular Weight: 291.144
• Hs Code.: 2913000090
• DSSTox Substance ID: DTXSID20353247
• Wikidata: Q82130719
• ChEMBL ID: CHEMBL2088930
• Mol file: 149833-95-4.mol

Synonyms:149833-95-4;4-(4-Bromobenzyloxy)benzaldehyde;4-[(4-bromophenyl)methoxy]benzaldehyde;4-[(4-bromobenzyl)oxy]benzaldehyde;4-((4-Bromobenzyl)oxy)benzaldehyde;4-[(4-Bromobenzyl)oxy]benzenecarbaldehyde;SCHEMBL865744;CHEMBL2088930;DTXSID20353247;BBL016401;MFCD02091001;STK200411;AKOS000188669;4-(4-Bromobenzyloxy)benzaldehyde, 96%;NCGC00341129-01;CS-0116522;FT-0643454;D82073;AB00289333-03;12P-045;A808962;SR-01000234959;J-008631;J-513157;SR-01000234959-1

Chemical Property of 4-(4-Bromobenzyloxy)benzaldehyde

Chemical Property:

• Vapor Pressure: 3.07E-07mmHg at 25°C
• Melting Point: 88-92 °C(lit.)
• Boiling Point: 419.3°Cat760mmHg
• Flash Point: 207.4°C
• PSA: 26.30000
• Density: 1.441g/cm³
• LogP: 3.84060
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 289.99424
• Heavy Atom Count: 17
• Complexity: 228

Purity/Quality:

97% ^*data from raw suppliers

4-[(4-Bromobenzyl)oxy]benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1COC2=CC=C(C=C2)C=O)Br

Technology Process of 4-(4-Bromobenzyloxy)benzaldehyde

There total 7 articles about 4-(4-Bromobenzyloxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.7%

→ 4-((4-bromobenzyl)oxy)benzaldehyde (149833-95-4)

Guidance literature:

With potassium carbonate; In acetone; at 60 ℃; for 5h;

Reference yield: 91.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 1-bromomethyl-4-bromobenzene (589-15-1) → 4-((4-bromobenzyl)oxy)benzaldehyde (149833-95-4)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 1h;

DOI:10.1021/jm200310q

Reference yield: 70.0%

4-bromobenzenemethanol (873-75-6) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-((4-bromobenzyl)oxy)benzaldehyde (149833-95-4)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.12.049

upstream raw materials:

4-hydroxy-benzaldehyde

1-bromomethyl-4-bromobenzene

p-bromobenzyl chloride

4-bromobenzenemethanol

Downstream raw materials:

3,5-bis(4-(4-bromobenzyloxy)benzylidene)piperidin-4-one

(4-((4-formylphenoxy)methyl)phenyl)boronic acid

[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

(4-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-yl)methyl)phenoxy)methyl)phenyl)boronic acid