heronamide C

Base Information

Chemical Name:heronamide C
CAS No.:1257083-94-5
Molecular Formula:C₂₉H₃₉NO₃
Molecular Weight:449.634
Hs Code.:

Synonyms:

Suppliers and Price of heronamide C

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Heronamide C
1mg
$ 513.00

TRC
HeronamideC
2.5mg
$ 440.00

TRC
HeronamideC
1mg
$ 220.00

Cayman Chemical
Heronamide C ≥95%
5mg
$ 896.00

Cayman Chemical
Heronamide C ≥95%
1mg
$ 199.00

Total 3 raw suppliers

Chemical Property of heronamide C

Chemical Property:

Purity/Quality:

>95% by HPLC ^*data from raw suppliers

Heronamide C ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Heronamide C is an unusual polyene macrocyclic lactam containing two isolated tetraene and triene chromophores. Heronamide C induces a unique reversible vacuolisation of mammalian tumour cells by an as yet unidentified mechanism. Heronamide C is an unusual polyene macrocyclic lactam.

Technology Process of heronamide C

There total 17 articles about heronamide C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1610971-57-7
C₄₁H₆₇NO₃Si₂

: 1257083-94-5
heronamide C

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.201301487

Reference yield:

: 1610971-40-8
C₁₇H₂₅N

: 1257083-94-5
heronamide C

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper(l) cyanide; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -30 °C / Inert atmosphere

1.2: 0.03 h / -25 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere

2.2: 0.33 h / 0 - 20 °C / Inert atmosphere; Darkness

3.1: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; n-butyllithium; tetrabutyl ammonium fluoride; copper(l) cyanide; acetic acid; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; 3.1: |Stille Cross Coupling;
DOI:10.1002/ejoc.201301487

Reference yield:

: 1610971-42-0
C₂₉H₅₃NSn

: 1257083-94-5
heronamide C

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere

1.2: 0.33 h / 0 - 20 °C / Inert atmosphere; Darkness

2.1: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; tetrabutyl ammonium fluoride; acetic acid; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide; 2.1: |Stille Cross Coupling;
DOI:10.1002/ejoc.201301487